HIV-1: maternal prognosis

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HIV-1: maternal prognosis.

Profound modifications in the profile of patients are currently being observed within the epidemic context of AIDS, especially with respect to pauperization and feminization of the disease. The population most frequently affected is in the reproductive age, and among adults aged 18 to 24 years, the ratio is 1 man to 1 woman, a phenomenon occurring uniformly all over the world. One of the main c...

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Breastfeeding and maternal HIV-1 disease progression and mortality.

OBJECTIVE To examine the association between breastfeeding and disease progression among HIV-infected women in Dar es Salaam, Tanzania. DESIGN AND METHODS Cohort study design with Cox proportional hazards models. RESULTS The relative risk of death comparing women who recently had been breastfeeding to those who were not breastfeeding was 0.47 (95% confidence interval, 0.18-1.20). Neither br...

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Maternal or infant antiretroviral drugs to reduce HIV-1 transmission.

BACKGROUND We evaluated the efficacy of a maternal triple-drug antiretroviral regimen or infant nevirapine prophylaxis for 28 weeks during breast-feeding to reduce postnatal transmission of human immunodeficiency virus type 1 (HIV-1) in Malawi. METHODS We randomly assigned 2369 HIV-1-positive, breast-feeding mothers with a CD4+ lymphocyte count of at least 250 cells per cubic millimeter and t...

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LOX-1 protein, A Biomarker in the Prognosis of Atherosclerosis

LOX-1 is a class E scavenger receptor that mediates the uptake of oxLDL by vascular cells. LOX-1 is involved in endothelial dysfunctions, monocyte adhesion, the proliferation, migration, and apoptosis of smooth muscle cells, foam cell formation, platelet activation, as well as plaque instability; all of these events are critical in the pathogenesis of atherosclerosis. These LOX-1-dependent bio...

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HIV and pregnancy: maternal and neonatal evolution.

Data regarding epidemiological aspects, antiretroviral drug safety, and outcomes of HIV-infected pregnant women and their newborns are limited in Argentina. We underwent a retrospective analysis of registries of HIV-infected pregnant women assisted at Helios Salud, Buenos Aires, Argentina (1997-2006). Variables associated with preterm delivery and neonatal complications were analyzed by univari...

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ژورنال

عنوان ژورنال: Revista do Hospital das Clínicas

سال: 2004

ISSN: 0041-8781

DOI: 10.1590/s0041-87812004000100005